Making gene editing a therapeutic reality

The reality of pharmacogenomics: optimizing therapeutic decision making.

is now well established that significant interindividual variability exists in the disposition and pharmacologic effects of certain medications. Influences such as environmental exposures, nutritional status, co-morbidities, severity of disease, and concomitant medications have all been associated with heterogeneity in drug responses. In addition, the profound contribution of genetics has been ...

Making Mobile Augmented Reality A Reality

Recent advances in mobile device technology have freed augmented reality (AR) applications from the constraints of desktops, laptops and head-mounted displays. But they are met with a lack of guidelines on the design and user interactions of mobile device-based AR systems. The situation for developers is further exacerbated by closed-license environments and inflexible solutions. We provide an ...

Making maritime TBMD a reality

Making Patient Engagement a Reality

Patients are increasingly recognised as the true customers of healthcare. By providing insights and perspectives, patients can help the wider healthcare community better understand their needs and ultimately enhance the value of healthcare solutions being developed. In the development of new medicines, for example, meaningful patient engagement can enable the pharmaceutical industry, healthcare...

Making virtual screening a reality.

T he discovery of new bioactive compounds for specific biomolecular targets represents a significant hurdle in the early stages of drug discovery. Advances in automation and bioanalytical methods have provided high-throughput screening (HTS) techniques that can perform individual biochemical assays on as many as a million compounds or more. Even with HTS, the discovery of new lead compounds lar...